Tuesday, 3 of September. First day of SENS6 or does eating less mean living longer

Friday, September 13, 2013 1 comments
Our team led by Alex Zhavoronkov arrived in Cambridge. Old Colleges among the wonderful scenery - you can not come up with a place for the conference better than it. 
We had a tight schedule and here I'll write about the most interesting lectures and meetings of each day.

Queen's College, Cambridge

First session was initiate into calorie restriction in primates and possibility of this strategy in human. 

Caloric restriction is a dietary regimen of reduced calorie intake without malnutrition which has been shown to hold aging up, according to 20 years of data.

Rozalyn Anderson from University of Wisconsin told us that factors involved in regulation of metabolism are likely to be important in the mechanism of lifespan extension. Aging is associated with slowing down of energy metabolism and decreased expression of mitochondrial genes. These suppositions baking a model where reprogramming of energy metabolism have a main role in the mechanisms of caloric restriction.

After that, Rozalyn Anderson and Donald Ingram from Pennington Biomedical Research Center were talking about different survival outcomes of two monkey caloric restriction studies: UW (University of Wisconsin) and NIA (National Institute on Aging). The reasons discussed there include genetic origin of the study hogort, feeding regimens, dietary composition and protocols for animal husbandry.

Photos of monkeys who participated in that studies have been demonstrated. Undoubtedly, calorie restriction provided a nice coat, elastic skin and more energetic behaviour. But in my opinion, the monkey that was kept on a diet looked a little bit nervous. I think that we are to look after their emotional status too because would they like to live longer in case they don't enjoy it?


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